gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0479 ::
FAMILY Phosphodiesterases
SUBFAMILY Rhodopsin-sensitive cGMP-specific PDEases
TYPE Phosphodiesterase 6

Cross References:
UniProt Q28263 | Q29470 EMBL Z68340 | U52868 | Y13282
InterPro IPR003018 | IPR003607 | IPR002073
GENEID 403620
PRINTS PR00387 PFAM PF01590 | PF00233

Details:
NAME Phosphodiesterase-6-Canis familiaris-5
DESCRIPTION Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(EC 3.1.4.35) (GMP-PDE alpha).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE PDE6A | PDEA
SEQUENCE
MGEVTAEQVEKFLDSNIIFAKQYYNLRYRAKVISDMLGAKEAAVDFSNYHSLSSVEESEI
IFDLLRDFQENLQAERCIFNVMKKLCFLLQADRMSLFMYRVRNGIAELATRLFNVHKDAV
LEECLVAPDSEIVFPLDMGVVGHVAHSKKIANVVNTEEDEHFCDFVDTLTEYQTKNILAS
PIMNGKDVVAVIMAVNKVDEPHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQI
LLWSGSKVFEELTDI
FRAGMENT NO
FUNCTION This protein participates in processes of transmissions and amplification of the visual signal
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15988071 | 14699118
1GPR0246Galpha-t1-Canis familiaris


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