gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0496 ::
FAMILY Phosphodiesterases
SUBFAMILY Rhodopsin-sensitive cGMP-specific PDEases
TYPE Phosphodiesterase 6

Cross References:
UniProt Q80UF0 EMBL AK044364
InterPro IPR003018 | IPR003607 | IPR002073
GENEID 18587
PRINTS PR00387 PFAM PF01590 | PF00233

Details:
NAME Phosphodiesterase-6-Mus musculus-10
DESCRIPTION Adult retina cDNA, RIKEN full-length enriched library,clone:A930009G18 product:phosphodiesterase 6B, cGMP, rod receptor,beta polypeptide, full insert sequence.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Pde6b
SEQUENCE
MSLSEEQVRSFLDGNPTFAHQYFGKKLSPENVAGACEDGWLADCGSLRELCQVEESAALF
ELVQDMQESVNMERVVFKILRRLCTILHADRCSLFMYRQRNGIAELATRLFSVQPDSLLE
DCLVPPDSEIVFPLDIGIVGHVAQTKKMINVQDVAECPHFSSFADELTDYVTKNILSTPI
MNGKDVVAVIMAVNKLDGPCFTSEDEDVFTKYLNFATLNLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIER
FRAGMENT NO
FUNCTION -
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15988071 | 14699118
1GPR0248Galpha-t1-Mus musculus
2GPR0251Galpha-t2-Mus musculus-2
3GPR0320Galpha-t2-Mus musculus-1
4GPR0381Galpha-t-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory