gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0056 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 8

Cross References:
UniProt P40145 EMBL Z35309 | M83533
InterPro IPR001054 | IPR009398
GENEID 114 MIM 103070
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-8-Homo sapiens-2
DESCRIPTION Adenylate cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type VIII)(ATP pyrophosphate-lyase 8) (Adenylyl cyclase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADCY8
SEQUENCE 
MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGS
GSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT
YLQYSGVVTWVAMTT
 FRAGMENT NO
FUNCTION This is a membrane-bound, calcium-stimulable adenylyls cyclase
Interacting with G-proteins:
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3

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