gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0691 ::
FAMILY Ser Thr protein kinases
SUBFAMILY RAF protein kinases
TYPE Raf1 protein kinase

Cross References:
UniProt P09560 | Q91390 EMBL X12948 | S74063
InterPro IPR002219 | IPR000719 | IPR003116 | IPR008271
PRODOM PD000001
PRINTS PR00008 PFAM PF00130 | PF00069 | PF02196

Details:
NAME Raf1 protein kinase-Xenopus laevis
DESCRIPTION RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (C-RAF).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE raf1 | raf
SEQUENCE 
MEHIQGAWKTLSNGFGFKESVFEGSSCMSPTIVHQFGYQRRASDDGKLSDTSKTSSTMRV
YLPNKQRTVVNVRSGMSLHDCLMKSLKVRGLQPECCAVFRLIQDPKGKLRLDWNTDAMSL
VGAELQVDFLDHVPLTTHNFVRKTFLKLAFCDICQKFLLNAFRCQTCGYKFHEHCSTKVP
TMCVDWSNIRQLLLFPNPNNIEGGSHTLPSLTMRRIGESVRIPVSSQQRYSTPHPFSFST
PSPVSECSLSQRQRS
 FRAGMENT NO
FUNCTION Involved in the transduction of mitogenic signals froms the cell membrane to the nucleus
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0151Gbeta-1-Xenopus laevis
2GPR0315Gbeta-2-Xenopus laevis
Family:Ggamma REFERENCES:15251227
3GPR0301Ggamma-7-Xenopus laevis
4GPR0316Ggamma-13-Xenopus laevis

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athina University of Athens
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