gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0072 ::
FAMILY Ion channels
SUBFAMILY ATP-sensitive inward rectifier potassium channels
TYPE ATP-sensitive inward rectifier potassium channel 10

Cross References:
UniProt P78508 | Q5VUT9 | Q8N4I7 | Q92808 EMBL U73192 | U73193 | U52155 | AL513302 | BC034036
InterPro IPR001838 | IPR003269 | IPR013521 | IPR013518
PRODOM PD001103 GENEID 3766 MIM 602208
PRINTS PR01322 | PR01320 PFAM PF01007

Details:
NAME ATP-sensitive inward rectifier potassium channel-10-Homo sapiens-2
DESCRIPTION ATP-sensitive inward rectifier potassium channel 10 (Potassiumchannel, inwardly rectifying subfamily J member 10) (Inward rectifierK(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassiumchannel Kir4.1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE KCNJ10
SEQUENCE 
MTSVAKVYYSQTTQTESRPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFI
DMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFL
FSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIR
FSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQV
DTASDSPFLILPLTF
 FRAGMENT NO
FUNCTION May be responsible for potassium buffering action ofs glial cells in the brain
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10990455
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 10990455
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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