gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1071 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P1

Cross References:
UniProt Q9PU17 | Q5D097 EMBL AJ249843 | BC049389
InterPro IPR002277 | IPR000276 | IPR004065 GPCRDB LPA11_XENLA
GENEID 379403
PRINTS PR01148 | PR00237 | PR01527 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P1_Xenopus laevis-1
DESCRIPTION Lysophosphatidic acid receptor LPA1 homolog 1 (xLPA1-1).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE lpa1r1 | lpa1r
SEQUENCE
MASLSEFVSEPISMMSQTSAASESQCYYNETIAFFYNRSGKYLATEWNAVSKLVMGLGIT
VCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTV
STWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTVAIVM
GAIPSVGWNCICDLEQCSNMAPLYSDSYLIFWTIFNLVTFVVMVVLYAHIFVYVRQKTMR
MSRHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDICCPQCNILAYEKFFLL
LAEFNSAMNPIIYSYRDKEMSATFKQILCCQRTENVNGPTEGSDRSASSLNHTILAGVHS
NDHSVV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9488656
1GPR0016Galpha-o-Xenopus laevis
2GPR0112Galpha-i3-Xenopus laevis
3GPR0222Galpha-i1-Xenopus laevis
4GPR0271Galpha-o1-Xenopus laevis
5GPR0272Galpha-i-Xenopus laevis


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory