| Details: |
| NAME |
ADENOSINE RECEPTOR_A1_Cavia porcellus |
| DESCRIPTION |
Adenosine receptor A1. |
| SPECIES |
Cavia porcellus |
COMMON NAME |
Guinea pig |
NCBI Taxonomy |
10141 |
| GENE |
ADORA1 |
| SEQUENCE |
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPEPPIDEDLPEEKVDD
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12123822
|
| HETERODIMER INFORMATION |
Forms heterodimers with Dopamine D1 Receptor. Heterodimerization results in altered D1 receptor signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10890919
|
| HETERODIMER INFORMATION |
Forms heterodimers with Metabotropic Glutamate Receptor 1. Dimerization results in alteration of signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11278325
|
| HETERODIMER INFORMATION |
Forms heterodimers with P2Y1 Receptors. Heterodimerization results in altered ligand binding
|
METHOD |
Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
11390975 | 12417330 | 12123822
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 1662665 | | 1 | GPR0107 | Galpha-i3-Cavia porcellus | | 2 | GPR0216 | Galpha-i1-Cavia porcellus | | 3 | GPR0224 | Galpha-i2-Cavia porcellus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
