gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1915 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY OPIOID AND OPIOID-LIKE RECEPTOR
SUBFAMILY N/OFQ RECEPTOR

Cross References:
UniProt P35377 | Q60645 | Q8VI74 | Q9QUT5 | Q9Z2M8 | Q9Z2M9 | Q9Z2N0 EMBL U04952 | D31667 | X91813 | U32932 | U32928 | U32930 | U09421 | AF043276 | AF043277 | AF043278 | AF062381 | AF075605 | AF126469 | BC050885 | U14165
InterPro IPR000276 | IPR001418 | IPR001420 GPCRDB OPRX_MOUSE
GENEID 18389
PRINTS PR00237 | PR00384 | PR00547 PFAM PF00001

Details:
NAME OPIOID AND OPIOID-LIKE RECEPTOR_N/OFQ RECEPTOR_Mus musculus
DESCRIPTION Nociceptin receptor (Orphanin FQ receptor) (Kappa-type 3 opioidreceptor) (KOR-3) (ORGC) (K3 opiate receptor).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Oprl1 | Oor | Oprl
SEQUENCE
MESLFPAPFWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCI
GGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALC
KTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGV
PVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLR
GVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRF
CTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVGLGCKTS
ETVPRPA
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15019559
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory