gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2364 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY OREXIN RECEPTOR
SUBFAMILY Orexin 1

Cross References:
UniProt P56718 EMBL AF041244
InterPro IPR000276 | IPR000204 | IPR004059 GPCRDB OX1R_RAT
GENEID 25593
PRINTS PR00237 | PR01521 | PR01064 PFAM PF00001

Details:
NAME OREXIN RECEPTOR_Orexin 1_Rattus norvegicus
DESCRIPTION Orexin receptor type 1 (Ox1r) (Hypocretin receptor type 1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Hcrtr1
SEQUENCE
MEPSATPGAQPGVPTSSGEPFHLPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFLIA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAVMVPQA
AVMECSSVLPELANRTRLFSVCDERWADELYPKIYHSCFFFVTYLAPLGLMGMAYFQIFR
KLWGPQIPGTTSALVRNWKRPSEQLEAQHQGLCTEPQPRARAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPSSSARHKSLSLQSRCSVSKVSEHVVLTTVTTVLS
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:9491897
1GPR0032Galpha-11-Rattus norvegicus
2GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
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Biophysics
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Laboratory