gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2413 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PLATELET ACTIVATING FACTOR (PAF) RECEPTOR
SUBFAMILY PLATELET ACTIVATING FACTOR (PAF) RECEPTOR

Cross References:
UniProt Q62035 | Q8C017 EMBL D50872 | AK032547
InterPro IPR000276 | IPR002282 GPCRDB PTAFR_MOUSE
GENEID 19204
PRINTS PR00237 | PR01153 PFAM PF00001

Details:
NAME PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_Mus musculus
DESCRIPTION Platelet-activating factor receptor (PAF-R).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Ptafr
SEQUENCE 
MEHNGSFRVDSEFRYTLFPIVYSVIFILGVVANGYVLWVFANLYPSKKLNEIKIFMVNLT
MADLLFLITLPLWIVYYYNEGDWILPNFLCNVAGCLFFINTYCSVAFLGVITYNRYQAVA
YPIKTAQATTRKRGISLSLIIWVSIVATASYFLATDSTNLVPNKDGSGNITRCFEHYEPY
SVPILVVHVFIAFCFFLVFFLIFYCNLVIIHTLLTQPMRQQRKAGVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFR
KHLSEKFYSMRSSRKCSRATSDTCTEVIVPANQTPIVSLKN
 FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 7929127

Coupling with G-proteins:
Family:Gi/o REFERENCES:7876256
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:7876256
6GPR0031Galpha-11-Mus musculus-2
7GPR0240Galpha-q-Mus musculus
8GPR0360Galpha-11-Mus musculus-1

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