gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2419 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY DP2

Cross References:
UniProt Q9Y5Y4 | O94765 | Q4QRI6 EMBL AF118265 | AB008535 | AF144308 | AY507142 | BC096841
InterPro IPR000826 | IPR000276 GPCRDB GPR44_HUMAN
MIM 604837
PRINTS PR00526 | PR00237 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_DP2_Homo sapiens
DESCRIPTION Putative G-protein coupled receptor 44 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (CD294 antigen).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GPR44 | CRTH2 | DL1R
SEQUENCE 
MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQAALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:12721327
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory