gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2459 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR2

Cross References:
UniProt P55086 EMBL Z48043
InterPro IPR000276 | IPR002281 | IPR003912 GPCRDB PAR2_MOUSE
PRINTS PR00237 | PR01428 | PR01152 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR2_Mus musculus
DESCRIPTION Proteinase-activated receptor 2 precursor (PAR-2) (Thrombin receptor-like 1) (Coagulation factor II receptor-like 1) (G-protein coupledreceptor 11).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE F2rl1 | Gpcr11 | Gpr11 | Par2
SEQUENCE
MRSLSLAWLLGGITLLAASVSCSRTENLAPGRNNSKGRSLIGRLETQPPITGKGVPVEPG
FSIDEFSASILTGKLTTVFLPVVYIIVFVIGLPSNGMALWIFLFRTKKKHPAVIYMANLA
LADLLSVIWFPLKISYHLHGNNWVYGEALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIV
NPMGHPRKKANIAVGVSLAIWLLIFLVTIPLYVMKQTIYIPALNITTCHDVLPEEVLVGD
MFNYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRQRAIRLIITVLAMYFI
CFAPSNLLLVVHYFLIKTQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDHARNA
LLCRSVRTVNRMQISLSSNKFSRKSGSYSSSSTSVKTSY
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15082510
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:15082510
6GPR0031Galpha-11-Mus musculus-2
7GPR0240Galpha-q-Mus musculus
8GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory