gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2461 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR2

Cross References:
UniProt P55085 | Q13317 | Q13346 EMBL Z49993 | Z49994 | U34038 | AF400075 | BC012453 | BC018130 | U36753
InterPro IPR000276 | IPR002281 | IPR003912 GPCRDB PAR2_HUMAN
GENEID 2150 MIM 600933
PRINTS PR00237 | PR01428 | PR01152 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR2_Homo sapiens
DESCRIPTION Proteinase-activated receptor 2 precursor (PAR-2) (Thrombin receptor-like 1) (Coagulation factor II receptor-like 1) (G-protein coupledreceptor 11).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE F2RL1 | GPR11 | PAR2
SEQUENCE 
MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15082510
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:15082510
8GPR0002Galpha-q-Homo sapiens-2
9GPR0029Galpha-11-Homo sapiens
10GPR0237Galpha-q-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory