gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2465 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR4

Cross References:
UniProt Q920E0 EMBL AF310216 | AF269246
InterPro IPR000276 | IPR003944 | IPR003912 GPCRDB PAR4_RAT
GENEID 116498
PRINTS PR00237 | PR01428 | PR01430 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR4_Rattus norvegicus
DESCRIPTION Proteinase-activated receptor 4 precursor (PAR-4) (Thrombin receptor-like 3) (Coagulation factor II receptor-like 3).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE F2rl3 | Par4
SEQUENCE
MCWPLLYPLMLGFSISPAECQTPSIYDDVESTREGQEASLRPTVELNESKSPDKPNPRGF
PGKPCANNSDTLELPASSEALLLGWVPTRLVPAIYGLVVVVGLPANGLALWVLATRVPRL
PSTILLMNLAVADLLLALVLPPRLVYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAA
VSLDRYLALVHSLRARALRGQRLTTILCLVAWLSAATLVLPLTFHRQTFLLAGSDRMLCH
DALPLAEQTSHWRPAFICLAVLGCFVPLLAMVLCYGATLRALAANGQRYSHAVRLTALVL
FSAVAAFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFRE
KVRAMLCRQLKASSSSQASREAGSRGTAICSSTLL
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15082510
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:15082510
5GPR0032Galpha-11-Rattus norvegicus
6GPR0242Galpha-q-Rattus norvegicus


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