gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2466 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR4

Cross References:
UniProt O88634 EMBL AF080215
InterPro IPR000276 | IPR003944 | IPR003912 GPCRDB PAR4_MOUSE
PRINTS PR00237 | PR01428 | PR01430 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR4_Mus musculus
DESCRIPTION Proteinase-activated receptor 4 precursor (PAR-4) (Thrombin receptor-like 3) (Coagulation factor II receptor-like 3).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE F2rl3 | Par4
SEQUENCE
MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRG
YPGKFCANDSDTLELPASSQALLLGWVSTRLVPALYGLVVAVGLPANGLALWVLATRVPR
LPSTILLTNLAVADSLLALVPPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLA
AVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLC
HDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALV
LFSAVASFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFR
EKVRAMLCRQPEASSSSQASREAGSRGTAICSSTLL
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15082510
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:15082510
6GPR0031Galpha-11-Mus musculus-2
7GPR0240Galpha-q-Mus musculus
8GPR0360Galpha-11-Mus musculus-1


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