gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2487 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY SOMATOSTATIN RECEPTOR
SUBFAMILY SST4

Cross References:
UniProt P31391 | Q17RM1 | Q9UIY1 EMBL D16826 | L14856 | L07833 | L07061 | AY548169 | AL049651 | BC069063 | BC117272
InterPro IPR000276 | IPR004047 | IPR000586 | IPR001512 GPCRDB SSR4_HUMAN
MIM 182454
PRINTS PR00237 | PR01507 | PR00246 | PR00590 PFAM PF00001

Details:
NAME SOMATOSTATIN RECEPTOR_SST4_Homo sapiens
DESCRIPTION Somatostatin receptor type 4 (SS4R).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE SSTR4
SEQUENCE 
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR
AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP
IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA
VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLVVTSLDATVNHVSLILS
YANSCANPILYGFLSDNFRRSFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM
CPPLPCQQEALQPEPGRKRIPLTRTTTF
 FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET) REFERENCES 10713101

Coupling with G-proteins:
Family:Gi/o REFERENCES:8483934
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
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