gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2500 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY TACHYKININ RECEPTOR
SUBFAMILY NK1

Cross References:
UniProt P30548 EMBL X62934 | L27828 | L27826
InterPro IPR000276 | IPR001681 | IPR000046 GPCRDB NK1R_MOUSE
PRINTS PR00237 | PR01024 | PR00244 PFAM PF00001

Details:
NAME TACHYKININ RECEPTOR_NK1_Mus musculus
DESCRIPTION Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykininreceptor 1).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Tacr1 | Tac1r
SEQUENCE 
MDNVLPVDSDLFPNTSTNTSESNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAH
KRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASI
YSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPSRVVC
MIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMY
NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQSSVYKVSRLETTIST
VVGAHEDEPEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNILA
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:8999927
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gq/11 REFERENCES:1370820
5GPR0031Galpha-11-Mus musculus-2
6GPR0240Galpha-q-Mus musculus
7GPR0360Galpha-11-Mus musculus-1
Family:Gs REFERENCES:1370820
8GPR0123Galpha-s-Mus musculus-2
9GPR0391Galpha-s-Mus musculus

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