gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2610 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY PARATHYROID HORMONE RECEPTOR
SUBFAMILY PARATHYROID HORMONE RECEPTOR

Cross References:
UniProt P49190 | Q8N429 EMBL U25128 | AY497546 | BC036811 | U47124 | U47129 | U47125 | U47126 | U47127 | U47128
InterPro IPR001879 | IPR000832 GPCRDB PTH2R_HUMAN
GENEID 5746 MIM 601469
PRINTS PR00249 PFAM PF00002 | PF02793

Details:
NAME PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE RECEPTOR_Homo sapiens
DESCRIPTION Parathyroid hormone 2 receptor precursor (PTH2 receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PTH2R | PTHR2
SEQUENCE 
MAGLGASLHVWGWLMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGE
GNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWA
NYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIH
MHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAV
VMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARAT
LADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRK
LAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEV
QAEVKKMWSRWNLSVDWKRTPPCGSRRCGSVLTTVTHSTSSQSQVAASTRMVLISGKAAK
IASRQPDSHITLPGYVWSNSEQDCLPHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTE
GCQGETEDVL
 FRAGMENT NO

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Scaffold:
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 12075354
TYPE NHERF2/E3 KARP REFERENCES 12075354

Coupling with G-proteins:
Family:Gs REFERENCES:7797535
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory