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gpDB::GPCR View
Entry 1 of 1 :: GPCR2661 ::
CLASS CLASS C (METABOTROPIC GLUTAMATE / PHEROMONE)
FAMILY GLUTAMATE RECEPTOR (METABOTROPIC)
SUBFAMILY MGLU6

Cross References:
UniProt P35349 EMBL D13963
InterPro IPR001828 | IPR000337 | IPR000162 | IPR000112 | IPR011500 GPCRDB GRM6_RAT
GENEID 24419
PRINTS PR00248 | PR01056 | PR00593 PFAM PF00003 | PF01094 | PF07562

Details:
NAME GLUTAMATE RECEPTOR (METABOTROPIC)_MGLU6_Rattus norvegicus
DESCRIPTION Metabotropic glutamate receptor 6 precursor (mGluR6).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Grm6 | Gprc1f | Mglur6
SEQUENCE
MGRLPVLLLWLAWWLSQAGIACGAGSVRLAGGLTLGGLFPVHARGAAGRACGALKKEQGV
HRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEA
SVRCPGGVPPLRSAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTR
YDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIA
QSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGS
DSWGSKISPILNLEEEAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFN
CKLTSSGGQSDDSTRKCTGEERIGQDSAYEQEGKVQFVIDAVYAIAHALHSMHQALCPGH
TGLCPAMEPTDGRTLLHYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGG
YQAVGQWAEALRLDMEVLRWSGDPHEVPPSQCSLPCGPGERKKMVKGVPCCWHCEACDGY
RFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLTWSSPWAALPLLLAVLGIMATTTIMAT
FMRHNDTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPCAAICAARRLLLGLGTTLSYS
ALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFGLTSLQVVGVIAWLGAQPPHSVID
YEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIG
FTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFH
PEQNVQKRKRSLKKTSTMAAPPQNENAEDAK
FRAGMENT NO

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Scaffold:
TYPE GRIP1( glutamate receptor interacting protein 1) REFERENCES 11891216
TYPE Syntenin REFERENCES 11891216

Coupling with G-proteins:
Family:Gi/o REFERENCES:8389366
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory