| Details: |
| NAME |
ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Homo sapiens |
| DESCRIPTION |
Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
ADRB1 | ADRB1R | B1AR |
| SEQUENCE |
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12140284 | 12244098
|
| HETERODIMER INFORMATION |
Forms heterodimers with B2 Adrenoceptors. Dimerization results in inhibiting internalization and ERK activation by B2 Adrenoceptor
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12244098
|
| HETERODIMER INFORMATION |
Forms heterodimers with B2 Adrenoceptors. Dimerization results in inhibiting internalization and ERK activation by B2 Adrenoceptor
|
METHOD |
Immunoprecipitation
|
REFERENCES |
12140284
|
| Scaffold: |
| TYPE |
CN-ras-GEF( cAMP-depented Ras exchange factor) /nRAP-GEP/RA-GEF
|
REFERENCES |
12391161
|
| TYPE |
Endophilin1-3( SH3p4,SH3p8,SH3p13)
|
REFERENCES |
10535961
|
| TYPE |
GIPC( GAIP-interacting protein)
|
REFERENCES |
12724327
|
| TYPE |
MAGI-2( membrane-associated guanylate kinase protein inverted 2) /S-SCAM
|
REFERENCES |
11526121
|
| TYPE |
Nck, Grb3
|
REFERENCES |
9843378 | 11384839
|
| TYPE |
PSD95( postsynaptic density protein)
|
REFERENCES |
10995758
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
