gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0397 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (B-ADRENOCEPTOR)
SUBFAMILY B3(Adrenoceptor)

Cross References:
UniProt P46626 | Q1LZC1 | Q28045 | Q9TS17 EMBL X85961 | AF109930 | BC116092 | X67214
InterPro IPR000681 | IPR002233 | IPR000276 GPCRDB ADRB3_BOVIN
GENEID 281606
PRINTS PR01103 | PR00563 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Bos taurus
DESCRIPTION Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE ADRB3
SEQUENCE
MAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIV
AIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRRALAAVVLVWVVSAAVSFAPIMSKWWRI
GADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRR
ELGRFPPEESPPAPSRSGSPGLAGPCASPAGVPSYGRRPARLLPLREHRALRTLGLIMGT
FTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCRPEEHLAAASPPRAPSGAPTALTSPAGPMQPPELDGASCGLS
FRAGMENT NO

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Scaffold:
TYPE c-Src REFERENCES 11013230

Coupling with G-proteins:
Family:Gi/o REFERENCES:9363896
1GPR0017Galpha-o1-Bos taurus
2GPR0219Galpha-i1-Bos taurus
3GPR0294Galpha-i2-Bos taurus-2
4GPR0295Galpha-i2-Bos taurus-1
Family:Gs REFERENCES:2570461
5GPR0114Galpha-s-Bos taurus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory