gpDB::GPCR View

gpDB: a database of GPCRs, G-proteins, Effectors and their interactions

gpDB::GPCR View

Entry 1 of 1 :: GPCR0478 ::

CLASS	CLASS A (RHODOPSIN LIKE)
FAMILY	CANNABINOID RECEPTOR
SUBFAMILY	CB1

Cross References:
UniProt	P21554 \| Q13949 \| Q495Z0 \| Q4PLI4 \| Q4VBM6 \| Q5UB37 \| Q9UNN0	EMBL	X54937 \| X81120 \| X81121 \| AY766182 \| AF107262 \| U73304 \| DQ067455 \| AY225225 \| AL136096 \| BC074811 \| BC074812 \| BC095513 \| BC100968 \| BC100969 \| BC100970 \| BC100971
InterPro	IPR002230 \| IPR000810 \| IPR000276	PDB	1LVQ \| 1LVR \| 2B0Y	GPCRDB	CNR1_HUMAN
GENEID	1268	MIM	114610
PRINTS	PR00522 \| PR00362 \| PR00237	PFAM	PF00001

Details:
NAME	CANNABINOID RECEPTOR_CB1_Homo sapiens-2
DESCRIPTION	Cannabinoid receptor 1 (CB1) (CB-R) (CANN6).
SPECIES	Homo sapiens	COMMON NAME	Human	NCBI Taxonomy	9606
GENE	CNR1 \| CNR
SEQUENCE	MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL				FRAGMENT	NO



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Scaffold:
TYPE	FAN( factor associated with neutral sphingomyelinase activation)			REFERENCES	11306675

Coupling with G-proteins:
Family:Gi/o		REFERENCES:	2165569
1	GPR0020	Galpha-o1-Homo sapiens
2	GPR0109	Galpha-i3-Homo sapiens
3	GPR0218	Galpha-i1-Homo sapiens-1
4	GPR0226	Galpha-i2-Homo sapiens-2
5	GPR0261	Galpha-i1-Homo sapiens-2
6	GPR0334	Galpha-o-Homo sapiens
7	GPR0365	Galpha-i2-Homo sapiens-1


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	University of Athens Faculty of Biology Dept. of Cell Biology and Biophysics	Biophysics & Bioinformatics Laboratory