gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0520 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CANNABINOID RECEPTOR
SUBFAMILY CB1

Cross References:
UniProt P20272 EMBL X55812 | U40395
InterPro IPR002230 | IPR000810 | IPR000276 GPCRDB CNR1_RAT
GENEID 25248
PRINTS PR00522 | PR00362 | PR00237 PFAM PF00001

Details:
NAME CANNABINOID RECEPTOR_CB1_Rattus norvegicus-1
DESCRIPTION Cannabinoid receptor 1 (CB1) (CB-R) (Brain-type cannabinoid receptor).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Cnr1 | Skr6
SEQUENCE
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
FRAGMENT NO

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Scaffold:
TYPE FAN( factor associated with neutral sphingomyelinase activation) REFERENCES 11306675

Coupling with G-proteins:
Family:Gi/o REFERENCES:2165569
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory