| Details: |
| NAME |
CHEMOKINE RECEPTOR (CC)_CCR5_Homo sapiens |
| DESCRIPTION |
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5)(HIV-1 fusion coreceptor) (CHEMR13) (CD195 antigen). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
CCR5 | CMKBR5 |
| SEQUENCE |
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12089144
|
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10725362
|
| HETERODIMER INFORMATION |
Forms heterodimers with Chemokine CCR2 Receptor. Dimerization increases the sensitivity and range of signalling pathways activated
|
METHOD |
Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
11350939
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
