gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0729 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY FMLP

Cross References:
UniProt P21462 | Q14939 | Q7Z6A4 | Q86U52 | Q9NS48 EMBL M37128 | M60626 | M60627 | L10820 | AY301273 | BT007429 | AC018755 | BC005315 | S49810
InterPro IPR015691 | IPR000826 | IPR000276 GPCRDB FPR1_HUMAN
GENEID 2357 MIM 136537
PRINTS PR00526 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_FMLP_Homo sapiens-2
DESCRIPTION fMet-Leu-Phe receptor (fMLP receptor) (N-formyl peptide receptor)(FPR) (N-formylpeptide chemoattractant receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE FPR1
SEQUENCE 
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFLFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVALQAK
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11160182
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
8GPR0128Galpha-z-Homo sapiens-2
9GPR0327Galpha-z-Homo sapiens-3
10GPR0333Galpha-z-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory