gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0752 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY DOPAMINE RECEPTOR
SUBFAMILY D1

Cross References:
UniProt Q9QZQ9 EMBL AF171079
InterPro IPR015694 | IPR000929 | IPR000276 GPCRDB Q9QZQ9_MOUSE
PRINTS PR00242 | PR00237 PFAM PF00001

Details:
NAME DOPAMINE RECEPTOR_D1_Mus musculus-2
DESCRIPTION D1A dopamine receptor .
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Drd1a | D1dr
SEQUENCE
MAPNTSTMDETGLPVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPF
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9804783
HETERODIMER INFORMATION Forms heterodimers with Adenosine A1 Receptor. Heterodimerization results in altered D1 receptor signalling METHOD Immunoprecipitation REFERENCES 10890919

Coupling with G-proteins:
Family:Gs REFERENCES:11238742
1GPR0104Galpha-olf-Mus musculus
2GPR0123Galpha-s-Mus musculus-2
3GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory