gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0807 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY DOPAMINE RECEPTOR
SUBFAMILY D5

Cross References:
UniProt P21918 | Q8NEQ8 EMBL X58454 | M67439 | AY136750 | BC009748
InterPro IPR015694 | IPR000497 | IPR000929 | IPR000276 GPCRDB DRD5_HUMAN
GENEID 1816 MIM 126453 | 606798
PRINTS PR00566 | PR00242 | PR00237 PFAM PF00001

Details:
NAME DOPAMINE RECEPTOR_D5_Homo sapiens
DESCRIPTION D(1B) dopamine receptor (D(5) dopamine receptor) (D1beta dopaminereceptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE DRD5 | DRD1B | DRD1L2
SEQUENCE
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVL
VCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFD
IMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNW
HRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAI
MIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSV
IMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYA
FNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTP
GNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:12623966
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gs REFERENCES:15082510
3GPR0103Galpha-olf-Homo sapiens-2
4GPR0310Galpha-olf-Homo sapiens-1
5GPR0119Galpha-s-Homo sapiens-2
6GPR0263Galpha-s-Homo sapiens-4
7GPR0266Galpha-s-Homo sapiens-5
8GPR0267Galpha-s-Homo sapiens-6
9GPR0277Galpha-s-Homo sapiens-7
10GPR0278Galpha-s-Homo sapiens
11GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory