gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::G-protein View
Entry 1 of 1 :: GPR0006 ::
CLASS Gbeta
FAMILY Gbeta
SUBFAMILY Gbeta
TYPE Gbeta-1

Cross References:
UniProt Q6TMK6 EMBL AY392427
InterPro IPR001632 | IPR015943 | IPR001680
PRODOM PD000018
PRINTS PR00319 | PR00320 PFAM PF00400

Details:
NAME Gbeta-1-Cricetulus griseus
DESCRIPTION Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(Transducin beta chain 1).
SPECIES Cricetulus griseus COMMON NAME Chinese hamster NCBI Taxonomy 10029
POST TRANSLATION MODIFICATIONS null GENE GNB1
SEQUENCE
MSELDQLRQEAEQLKNQIRDARKACADATLSXITTNIDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLNDNQIVTSSEDTTCALWDIETGQQTTTF
TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Effectors:
1EFF0571PI3K alpha-Cricetulus griseusPropable Inhibition16182515
2EFF0576PI3K beta-Cricetulus griseusActivation9305878 | 12502714
3EFF1017Tubulin-Cricetulus griseus-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
4EFF1018Tubulin-Cricetulus griseus-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
5EFF1019Tubulin-Cricetulus griseus-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
6EFF1020Tubulin-Cricetulus griseus-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
7EFF1021Tubulin-Cricetulus griseus-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
8EFF1022Tubulin-Cricetulus griseus-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
9EFF1023Tubulin-Cricetulus griseus-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
10EFF1024Tubulin-Cricetulus griseus-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
11EFF1025Tubulin-Cricetulus griseus-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086

Coupling with GPCRs:
No information




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